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Neutralization of chemokine-like factor 1, a novel C-C chemokine, protects against focal cerebral ischemia by inhibiting neutrophil infiltration via MAPK pathways in rats

BACKGROUND: Inflammation plays a key role in the pathophysiology of ischemic stroke. Some proinflammatory mediators, such as cytokines and chemokines, are produced in stroke. Chemokine-like factor 1 (CKLF1), as a novel C-C chemokine, displays chemotactic activities in a wide spectrum of leukocytes a...

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Detalles Bibliográficos
Autores principales: Kong, Ling Lei, Wang, Zhi Yuan, Han, Ning, Zhuang, Xiao Mei, Wang, Zhen Zhen, Li, Hua, Chen, Nai Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080607/
https://www.ncbi.nlm.nih.gov/pubmed/24946684
http://dx.doi.org/10.1186/1742-2094-11-112