Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung

We report a case of gefitinib-induced skin ulceration in a 50-year-old female with metastatic adenocarcinoma of lung who developed this adverse effect 2 weeks following initiation of gefitinib at a dose of 250 mg/day. The ulcer improved with stopping gefitinib for 2 weeks and also addition of topica...

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Autores principales: Sathyanarayanan, Vishwanath, Lokesh, Kadabur Nagendrappa, Channaviriappa, Lakshmaiah Kuntejowdahalli, Jacob, Linu Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080647/
https://www.ncbi.nlm.nih.gov/pubmed/25006299
http://dx.doi.org/10.4103/0971-5851.133736
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author Sathyanarayanan, Vishwanath
Lokesh, Kadabur Nagendrappa
Channaviriappa, Lakshmaiah Kuntejowdahalli
Jacob, Linu Abraham
author_facet Sathyanarayanan, Vishwanath
Lokesh, Kadabur Nagendrappa
Channaviriappa, Lakshmaiah Kuntejowdahalli
Jacob, Linu Abraham
author_sort Sathyanarayanan, Vishwanath
collection PubMed
description We report a case of gefitinib-induced skin ulceration in a 50-year-old female with metastatic adenocarcinoma of lung who developed this adverse effect 2 weeks following initiation of gefitinib at a dose of 250 mg/day. The ulcer improved with stopping gefitinib for 2 weeks and also addition of topical steroids and antibiotics. We are reporting this case to create awareness among treating oncologists of this adverse effect and also prompt interruption of therapy and topical steroids/antibiotics is useful to treat this adverse event.
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spelling pubmed-40806472014-07-08 Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung Sathyanarayanan, Vishwanath Lokesh, Kadabur Nagendrappa Channaviriappa, Lakshmaiah Kuntejowdahalli Jacob, Linu Abraham Indian J Med Paediatr Oncol Case Report We report a case of gefitinib-induced skin ulceration in a 50-year-old female with metastatic adenocarcinoma of lung who developed this adverse effect 2 weeks following initiation of gefitinib at a dose of 250 mg/day. The ulcer improved with stopping gefitinib for 2 weeks and also addition of topical steroids and antibiotics. We are reporting this case to create awareness among treating oncologists of this adverse effect and also prompt interruption of therapy and topical steroids/antibiotics is useful to treat this adverse event. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4080647/ /pubmed/25006299 http://dx.doi.org/10.4103/0971-5851.133736 Text en Copyright: © Indian Journal of Medical and Paediatric Oncology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sathyanarayanan, Vishwanath
Lokesh, Kadabur Nagendrappa
Channaviriappa, Lakshmaiah Kuntejowdahalli
Jacob, Linu Abraham
Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung
title Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung
title_full Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung
title_fullStr Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung
title_full_unstemmed Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung
title_short Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung
title_sort gefitinib-induced skin ulceration in metastatic adenocarcinoma lung
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080647/
https://www.ncbi.nlm.nih.gov/pubmed/25006299
http://dx.doi.org/10.4103/0971-5851.133736
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AT channaviriappalakshmaiahkuntejowdahalli gefitinibinducedskinulcerationinmetastaticadenocarcinomalung
AT jacoblinuabraham gefitinibinducedskinulcerationinmetastaticadenocarcinomalung

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