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Carcinomatous meningitis in non-small cell lung cancer: Palliation with intrathecal treatment

Carcinomatous meningitis or meningeal carcinomatosis is seen in up to 5% of patients of metastatic non-small cell lung cancer. However, isolated carcinomatous meningitis without brain parenchymal metastasis is less common. Patients with carcinomatous meningitis have limited treatment options. Howeve...

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Detalles Bibliográficos
Autores principales: Kumar, D. Santhosh, Noronha, Vanita, Joshi, Amit, Jain, Hasmukh, Prabhash, Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080668/
https://www.ncbi.nlm.nih.gov/pubmed/25006289
http://dx.doi.org/10.4103/0971-5851.133726
Descripción
Sumario:Carcinomatous meningitis or meningeal carcinomatosis is seen in up to 5% of patients of metastatic non-small cell lung cancer. However, isolated carcinomatous meningitis without brain parenchymal metastasis is less common. Patients with carcinomatous meningitis have limited treatment options. However, intrathecal therapy if used optimally along with targeted therapy when indicated result in good palliation with improvement in survival.