Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature

A 6½-year-old boy had developed acute lymphoblastic leukemia and was treated with systemic chemotherapy, intrathecal triple drug regimen and prophylactic cranial irradiation. After 10 years he developed anaplastic astrocytoma of the postero-superior cerebellum on the left side while leukemia was in...

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Autores principales: Ahmed, Imtiaz, Krishnamurthy, Sapna, Kakkar, Aanchal, Julka, Pramod Kumar, Rath, Goura Kishor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080671/
https://www.ncbi.nlm.nih.gov/pubmed/25006292
http://dx.doi.org/10.4103/0971-5851.133729
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author Ahmed, Imtiaz
Krishnamurthy, Sapna
Kakkar, Aanchal
Julka, Pramod Kumar
Rath, Goura Kishor
author_facet Ahmed, Imtiaz
Krishnamurthy, Sapna
Kakkar, Aanchal
Julka, Pramod Kumar
Rath, Goura Kishor
author_sort Ahmed, Imtiaz
collection PubMed
description A 6½-year-old boy had developed acute lymphoblastic leukemia and was treated with systemic chemotherapy, intrathecal triple drug regimen and prophylactic cranial irradiation. After 10 years he developed anaplastic astrocytoma of the postero-superior cerebellum on the left side while leukemia was in remission. He was treated with surgical excision, followed by adjuvant three dimensional conformal radiotherapy and is on salvage chemotherapy with temozolamide. It is possible that the anaplastic astrocytoma may be a radiation induced malignancy.
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spelling pubmed-40806712014-07-08 Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature Ahmed, Imtiaz Krishnamurthy, Sapna Kakkar, Aanchal Julka, Pramod Kumar Rath, Goura Kishor Indian J Med Paediatr Oncol Case Report A 6½-year-old boy had developed acute lymphoblastic leukemia and was treated with systemic chemotherapy, intrathecal triple drug regimen and prophylactic cranial irradiation. After 10 years he developed anaplastic astrocytoma of the postero-superior cerebellum on the left side while leukemia was in remission. He was treated with surgical excision, followed by adjuvant three dimensional conformal radiotherapy and is on salvage chemotherapy with temozolamide. It is possible that the anaplastic astrocytoma may be a radiation induced malignancy. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4080671/ /pubmed/25006292 http://dx.doi.org/10.4103/0971-5851.133729 Text en Copyright: © Indian Journal of Medical and Paediatric Oncology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ahmed, Imtiaz
Krishnamurthy, Sapna
Kakkar, Aanchal
Julka, Pramod Kumar
Rath, Goura Kishor
Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature
title Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature
title_full Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature
title_fullStr Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature
title_full_unstemmed Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature
title_short Primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: Case report and review of the literature
title_sort primary anaplastic astrocytoma of the brain after prophylactic cranial irradiation in a case of acute lymphoblastic leukemia: case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080671/
https://www.ncbi.nlm.nih.gov/pubmed/25006292
http://dx.doi.org/10.4103/0971-5851.133729
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