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Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases

DHH superfamily includes RecJ, nanoRNases (NrnA), cyclic nucleotide phosphodiesterases and pyrophosphatases. In this study, we have carried out in vitro and in vivo investigations on the bifunctional NrnA-homolog from Mycobacterium smegmatis, MSMEG_2630. The crystal structure of MSMEG_2630 was deter...

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Detalles Bibliográficos
Autores principales:	Srivastav, Rajpal, Kumar, Dilip, Grover, Amit, Singh, Ajit, Manjasetty, Babu A., Sharma, Rakesh, Taneja, Bhupesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081065/ https://www.ncbi.nlm.nih.gov/pubmed/24878921 http://dx.doi.org/10.1093/nar/gku425

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