eIF4B, eIF4G and RNA regulate eIF4A activity in translation initiation by modulating the eIF4A conformational cycle

Eukaryotic translation initiation factor eIF4A is a DEAD-box helicase that resolves secondary structure elements in the 5'-UTR of mRNAs during ribosome scanning. Its RNA-stimulated ATPase and ATP-dependent helicase activities are enhanced by other translation initiation factors, but the underly...

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Detalles Bibliográficos
Autores principales: Harms, Ulf, Andreou, Alexandra Zoi, Gubaev, Airat, Klostermeier, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081068/
https://www.ncbi.nlm.nih.gov/pubmed/24848014
http://dx.doi.org/10.1093/nar/gku440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081068/
https://www.ncbi.nlm.nih.gov/pubmed/24848014
http://dx.doi.org/10.1093/nar/gku440

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