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Jumonji domain containing protein 6 (Jmjd6) modulates splicing and specifically interacts with arginine–serine-rich (RS) domains of SR- and SR-like proteins

The Fe(II) and 2-oxoglutarate dependent oxygenase Jmjd6 has been shown to hydroxylate lysine residues in the essential splice factor U2 auxiliary factor 65 kDa subunit (U2AF65) and to act as a modulator of alternative splicing. We describe further evidence for the role of Jmjd6 in the regulation of...

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Detalles Bibliográficos
Autores principales:	Heim, Astrid, Grimm, Christina, Müller, Udo, Häußler, Simon, Mackeen, Mukram M., Merl, Juliane, Hauck, Stefanie M., Kessler, Benedikt M., Schofield, Christopher J., Wolf, Alexander, Böttger, Angelika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081092/ https://www.ncbi.nlm.nih.gov/pubmed/24914048 http://dx.doi.org/10.1093/nar/gku488

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