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Dynamic condensation of linker histone C-terminal domain regulates chromatin structure

The basic and intrinsically disordered C-terminal domain (CTD) of the linker histone (LH) is essential for chromatin compaction. However, its conformation upon nucleosome binding and its impact on chromatin organization remain unknown. Our mesoscale chromatin model with a flexible LH CTD captures a...

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Detalles Bibliográficos
Autores principales:	Luque, Antoni, Collepardo-Guevara, Rosana, Grigoryev, Sergei, Schlick, Tamar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081093/ https://www.ncbi.nlm.nih.gov/pubmed/24906881 http://dx.doi.org/10.1093/nar/gku491

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