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Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA

AbaSI, a member of the PvuRts1I-family of modification-dependent restriction endonucleases, cleaves deoxyribonucleic acid (DNA) containing 5-hydroxymethylctosine (5hmC) and glucosylated 5hmC (g5hmC), but not DNA containing unmodified cytosine. AbaSI has been used as a tool for mapping the genomic lo...

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Detalles Bibliográficos
Autores principales:	Horton, John R., Borgaro, Janine G., Griggs, Rose M., Quimby, Aine, Guan, Shengxi, Zhang, Xing, Wilson, Geoffrey G., Zheng, Yu, Zhu, Zhenyu, Cheng, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081097/ https://www.ncbi.nlm.nih.gov/pubmed/24895434 http://dx.doi.org/10.1093/nar/gku497

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