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TtcA a new tRNA-thioltransferase with an Fe-S cluster

TtcA catalyzes the post-transcriptional thiolation of cytosine 32 in some tRNAs. The enzyme from Escherichia coli was homologously overexpressed in E. coli. The purified enzyme is a dimer containing an iron–sulfur cluster and displays activity in in vitro assays. The type and properties of the clust...

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Detalles Bibliográficos
Autores principales: Bouvier, Denis, Labessan, Natty, Clémancey, Martin, Latour, Jean-Marc, Ravanat, Jean-Luc, Fontecave, Marc, Atta, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081106/
https://www.ncbi.nlm.nih.gov/pubmed/24914049
http://dx.doi.org/10.1093/nar/gku508

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