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Downregulation of CD40 expression contributes to the accumulation of myeloid-derived suppressor cells in gastric tumors
An elevated number of myeloid-derived suppressor cells (MDSCs) in tumor-bearing hosts has been recognized as a crucial mediator of tumor progression due to the cells potent ability to suppress antitumor immunity. Cluster of differentiation (CD) 40, as a suppressive phenotype expressed in MDSCs, is e...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081434/ https://www.ncbi.nlm.nih.gov/pubmed/25009656 http://dx.doi.org/10.3892/ol.2014.2174 |