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Downregulation of CD40 expression contributes to the accumulation of myeloid-derived suppressor cells in gastric tumors

An elevated number of myeloid-derived suppressor cells (MDSCs) in tumor-bearing hosts has been recognized as a crucial mediator of tumor progression due to the cells potent ability to suppress antitumor immunity. Cluster of differentiation (CD) 40, as a suppressive phenotype expressed in MDSCs, is e...

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Detalles Bibliográficos
Autores principales:	SHEN, JIN, CHEN, XIAOJUAN, WANG, ZHENXING, ZHANG, GUANGBO, CHEN, WEICHANG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081434/ https://www.ncbi.nlm.nih.gov/pubmed/25009656 http://dx.doi.org/10.3892/ol.2014.2174

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