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High glucose increases LPS-induced DC apoptosis through modulation of ERK1/2, AKT and Bax/Bcl-2

BACKGROUND: This study investigates the effect of glucose on the LPS-induced apoptosis of dendritic cells in the intestinal tract of mice and the dendritic cell line DC2.4. METHODS: Flow cytometry was used to detect dendritic cell apoptosis both in vivo and in vitro. Hoechst 33258 staining was used...

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Detalles Bibliográficos
Autores principales:	Feng, Mei, Li, Juan, Wang, Jun, Ma, Chunyan, Jiao, Yulian, Wang, Yan, Zhang, Jie, Sun, Qiuying, Ju, Ying, Gao, Ling, Zhao, Yueran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081508/ https://www.ncbi.nlm.nih.gov/pubmed/24885625 http://dx.doi.org/10.1186/1471-230X-14-98

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