Exome Sequencing from Nanogram Amounts of Starting DNA: Comparing Three Approaches

Hybridization-based target enrichment protocols require relatively large starting amounts of genomic DNA, which is not always available. Here, we tested three approaches to pre-capture library preparation starting from 10 ng of genomic DNA: (i and ii) whole-genome amplification of DNA samples with R...

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Detalles Bibliográficos
Autores principales: Rykalina, Vera N., Shadrin, Alexey A., Amstislavskiy, Vyacheslav S., Rogaev, Evgeny I., Lehrach, Hans, Borodina, Tatiana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081514/
https://www.ncbi.nlm.nih.gov/pubmed/24992588
http://dx.doi.org/10.1371/journal.pone.0101154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081514/
https://www.ncbi.nlm.nih.gov/pubmed/24992588
http://dx.doi.org/10.1371/journal.pone.0101154

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