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Guanylyl Cyclase-G Modulates Jejunal Apoptosis and Inflammation in Mice with Intestinal Ischemia and Reperfusion

BACKGROUND: Membrane bound guanylyl cyclase-G (mGC-G), a novel form of GC mediates ischemia and reperfusion (IR)-induced renal injury. We investigated the roles of mGC-G in intestinal IR-induced jejunal damage, inflammation, and apoptosis. MATERIALS AND METHODS: Male C57BL/6 wild-type (WT) and mGC-G...

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Detalles Bibliográficos
Autores principales: Lo, Hui-Chen, Yang, Ruey-Bing, Lee, Chien-Hsing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081647/
https://www.ncbi.nlm.nih.gov/pubmed/24992336
http://dx.doi.org/10.1371/journal.pone.0101314