Single-Nucleotide Mutation Matrix: A New Model for Predicting the NF-κB DNA Binding Sites

In this study, we established a single nucleotide mutation matrix (SNMM) model based on the relative binding affinities of NF-κB p50 homodimer to a wild-type binding site (GGGACTTTCC) and its all single-nucleotide mutants detected with the double-stranded DNA microarray. We evaluated this model by s...

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Detalles Bibliográficos
Autores principales: Du, Wenxin, Gao, Jing, Wang, Tingting, Wang, Jinke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081663/
https://www.ncbi.nlm.nih.gov/pubmed/24992458
http://dx.doi.org/10.1371/journal.pone.0101490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081663/
https://www.ncbi.nlm.nih.gov/pubmed/24992458
http://dx.doi.org/10.1371/journal.pone.0101490

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