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Single-Nucleotide Mutation Matrix: A New Model for Predicting the NF-κB DNA Binding Sites
In this study, we established a single nucleotide mutation matrix (SNMM) model based on the relative binding affinities of NF-κB p50 homodimer to a wild-type binding site (GGGACTTTCC) and its all single-nucleotide mutants detected with the double-stranded DNA microarray. We evaluated this model by s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081663/ https://www.ncbi.nlm.nih.gov/pubmed/24992458 http://dx.doi.org/10.1371/journal.pone.0101490 |