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Endothelial Nitric Oxide Synthase and Superoxide Mediate Hemodynamic Initiation of Intracranial Aneurysms
BACKGROUND: Hemodynamic insults at arterial bifurcations are believed to play a critical role in initiating intracranial aneurysms. Recent studies in a rabbit model indicate that aneurysmal damage initiates under specific wall shear stress conditions when smooth muscle cells (SMCs) become pro-inflam...
Autores principales: | Liaw, Nicholas, Dolan Fox, Jennifer M., Siddiqui, Adnan H., Meng, Hui, Kolega, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081806/ https://www.ncbi.nlm.nih.gov/pubmed/24992254 http://dx.doi.org/10.1371/journal.pone.0101721 |
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