The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins

The Dot/Icm system of the intracellular pathogen Legionella pneumophila has the capacity to deliver over 270 effector proteins into host cells during infection. Important questions remain as to spatial and temporal mechanisms used to regulate such a large array of virulence determinants after they h...

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Detalles Bibliográficos
Autores principales: Hubber, Andree, Arasaki, Kohei, Nakatsu, Fubito, Hardiman, Camille, Lambright, David, De Camilli, Pietro, Nagai, Hiroki, Roy, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081824/
https://www.ncbi.nlm.nih.gov/pubmed/24992562
http://dx.doi.org/10.1371/journal.ppat.1004222

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