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Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic Caboxamycin

Streptomyces sp. strain NTK 937 is the producer of the benzoxazole antibiotic caboxamycin, which has been shown to exert inhibitory activity against Gram-positive bacteria, cytotoxic activity against several human tumor cell lines, and inhibition of the enzyme phosphodiesterase. In this genome annou...

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Autores principales: Olano, Carlos, Cano-Prieto, Carolina, Losada, Armando A., Bull, Alan T., Goodfellow, Michael, Fiedler, Hans-Peter, Méndez, Carmen, Salas, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081993/
https://www.ncbi.nlm.nih.gov/pubmed/24994793
http://dx.doi.org/10.1128/genomeA.00534-14
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author Olano, Carlos
Cano-Prieto, Carolina
Losada, Armando A.
Bull, Alan T.
Goodfellow, Michael
Fiedler, Hans-Peter
Méndez, Carmen
Salas, José A.
author_facet Olano, Carlos
Cano-Prieto, Carolina
Losada, Armando A.
Bull, Alan T.
Goodfellow, Michael
Fiedler, Hans-Peter
Méndez, Carmen
Salas, José A.
author_sort Olano, Carlos
collection PubMed
description Streptomyces sp. strain NTK 937 is the producer of the benzoxazole antibiotic caboxamycin, which has been shown to exert inhibitory activity against Gram-positive bacteria, cytotoxic activity against several human tumor cell lines, and inhibition of the enzyme phosphodiesterase. In this genome announcement, we present a draft genome sequence of Streptomyces sp. NTK 937 in which we identified at least 35 putative secondary metabolite biosynthetic gene clusters.
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spelling pubmed-40819932014-07-16 Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic Caboxamycin Olano, Carlos Cano-Prieto, Carolina Losada, Armando A. Bull, Alan T. Goodfellow, Michael Fiedler, Hans-Peter Méndez, Carmen Salas, José A. Genome Announc Prokaryotes Streptomyces sp. strain NTK 937 is the producer of the benzoxazole antibiotic caboxamycin, which has been shown to exert inhibitory activity against Gram-positive bacteria, cytotoxic activity against several human tumor cell lines, and inhibition of the enzyme phosphodiesterase. In this genome announcement, we present a draft genome sequence of Streptomyces sp. NTK 937 in which we identified at least 35 putative secondary metabolite biosynthetic gene clusters. American Society for Microbiology 2014-07-03 /pmc/articles/PMC4081993/ /pubmed/24994793 http://dx.doi.org/10.1128/genomeA.00534-14 Text en Copyright © 2014 Olano et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Olano, Carlos
Cano-Prieto, Carolina
Losada, Armando A.
Bull, Alan T.
Goodfellow, Michael
Fiedler, Hans-Peter
Méndez, Carmen
Salas, José A.
Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic Caboxamycin
title Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic Caboxamycin
title_full Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic Caboxamycin
title_fullStr Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic Caboxamycin
title_full_unstemmed Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic Caboxamycin
title_short Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic Caboxamycin
title_sort draft genome sequence of marine actinomycete streptomyces sp. strain ntk 937, producer of the benzoxazole antibiotic caboxamycin
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081993/
https://www.ncbi.nlm.nih.gov/pubmed/24994793
http://dx.doi.org/10.1128/genomeA.00534-14
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