PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

Retinoids are micronutrients that are stored as retinyl esters in the retina and hepatic stellate cells (HSCs). HSCs are key players in fibrogenesis in chronic liver diseases. The enzyme responsible for hydrolysis and release of retinyl esters from HSCs is unknown and the relationship between retino...

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Detalles Bibliográficos
Autores principales: Pirazzi, Carlo, Valenti, Luca, Motta, Benedetta Maria, Pingitore, Piero, Hedfalk, Kristina, Mancina, Rosellina Margherita, Burza, Maria Antonella, Indiveri, Cesare, Ferro, Yvelise, Montalcini, Tiziana, Maglio, Cristina, Dongiovanni, Paola, Fargion, Silvia, Rametta, Raffaela, Pujia, Arturo, Andersson, Linda, Ghosal, Saswati, Levin, Malin, Wiklund, Olov, Iacovino, Michelina, Borén, Jan, Romeo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082369/
https://www.ncbi.nlm.nih.gov/pubmed/24670599
http://dx.doi.org/10.1093/hmg/ddu121

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