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Rac2 is involved in bleomycin-induced lung inflammation leading to pulmonary fibrosis
BACKGROUND: Pulmonary fibrotic diseases induce significant morbidity and mortality, for which there are limited therapeutic options available. Rac2, a ras-related guanosine triphosphatase expressed mainly in hematopoietic cells, is a crucial molecule regulating a diversity of mast cell, macrophage,...
Autores principales: | Arizmendi, Narcy, Puttagunta, Lakshmi, Chung, Kerri L, Davidson, Courtney, Rey-Parra, Juliana, Chao, Danny V, Thebaud, Bernard, Lacy, Paige, Vliagoftis, Harissios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082672/ https://www.ncbi.nlm.nih.gov/pubmed/24970330 http://dx.doi.org/10.1186/1465-9921-15-71 |
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