Themis2 Is Not Required for B Cell Development, Activation, and Antibody Responses

Themis1 is a protein implicated in transducing signals from the TCR. Mice deficient in Themis1 show a strong impairment in T cell selection in the thymus and defective T cell activation. The related Themis2 protein is expressed in B cells where it associates with signaling proteins Grb2 and Vav1, an...

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Detalles Bibliográficos
Autores principales: Hartweger, Harald, Schweighoffer, Edina, Davidson, Sophia, Peirce, Matthew J., Wack, Andreas, Tybulewicz, Victor L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2014
Materias:
Immune System Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082722/
https://www.ncbi.nlm.nih.gov/pubmed/24907343
http://dx.doi.org/10.4049/jimmunol.1400943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082722/
https://www.ncbi.nlm.nih.gov/pubmed/24907343
http://dx.doi.org/10.4049/jimmunol.1400943

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