Cargando…

Themis2 Is Not Required for B Cell Development, Activation, and Antibody Responses

Themis1 is a protein implicated in transducing signals from the TCR. Mice deficient in Themis1 show a strong impairment in T cell selection in the thymus and defective T cell activation. The related Themis2 protein is expressed in B cells where it associates with signaling proteins Grb2 and Vav1, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hartweger, Harald, Schweighoffer, Edina, Davidson, Sophia, Peirce, Matthew J., Wack, Andreas, Tybulewicz, Victor L. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2014
Materias:	Immune System Development
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082722/ https://www.ncbi.nlm.nih.gov/pubmed/24907343 http://dx.doi.org/10.4049/jimmunol.1400943

Ejemplares similares

The Transcription Factor E4BP4 Is Not Required for Extramedullary Pathways of NK Cell Development
por: Crotta, Stefania, et al.
Publicado: (2014)

Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive αβT Cells in the Adult Thymus
por: Cowan, Jennifer E., et al.
Publicado: (2014)

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7(+) Progenitors to the Thymus
por: Cosway, Emilie J., et al.
Publicado: (2018)

SSB1/SSB2 Proteins Safeguard B Cell Development by Protecting the Genomes of B Cell Precursors
por: Pfeifer, Matthias, et al.
Publicado: (2019)

Rapid CD4(+) T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9
por: Atif, Shaikh M, et al.
Publicado: (2015)

An Essential Role for Medullary Thymic Epithelial Cells during the Intrathymic Development of Invariant NKT Cells
por: White, Andrea J., et al.
Publicado: (2014)

Osteoprotegerin-Mediated Homeostasis of Rank(+) Thymic Epithelial Cells Does Not Limit Foxp3(+) Regulatory T Cell Development
por: McCarthy, Nicholas I., et al.
Publicado: (2015)

Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus
por: Pridans, Clare, et al.
Publicado: (2018)

APRIL Drives a Coordinated but Diverse Response as a Foundation for Plasma Cell Longevity
por: Stephenson, Sophie, et al.
Publicado: (2022)

Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk
por: White, Andrea J., et al.
Publicado: (2023)

The PDK1–Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning
por: Zaru, Rossana, et al.
Publicado: (2015)

Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus
por: Lucas, Beth, et al.
Publicado: (2016)

Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival
por: Müller-Winkler, Jennifer, et al.
Publicado: (2020)

A Csf1r-EGFP Transgene Provides a Novel Marker for Monocyte Subsets in Sheep
por: Pridans, Clare, et al.
Publicado: (2016)

ERK Signaling Controls Innate-like CD8(+) T Cell Differentiation via the ELK4 (SAP-1) and ELK1 Transcription Factors
por: Maurice, Diane, et al.
Publicado: (2018)

Adaptive from Innate: Human IFN-γ(+)CD4(+) T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults
por: Das, Abhishek, et al.
Publicado: (2017)

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors
por: Dennehy, Kevin M, et al.
Publicado: (2008)

Syk Tyrosine Kinase Is Critical for B Cell Antibody Responses and Memory B Cell Survival
por: Ackermann, Jochen A., et al.
Publicado: (2015)

TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK
por: Schweighoffer, Edina, et al.
Publicado: (2017)

The effect of the sympathetic nervous system on splenic natural killer cell activity in mice administered the Lactobacillus pentosus strain S-PT84
por: Izumo, Takayuki, et al.
Publicado: (2013)

BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival
por: Jacque, Emilie, et al.
Publicado: (2015)

The THEMIS Mission
por: Burch, J. L, et al.
Publicado: (2009)

Themis : nueva generación /
Publicado: (2010)

B cell–intrinsic requirement for WNK1 kinase in antibody responses in mice
por: Hayward, Darryl A., et al.
Publicado: (2023)

IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell–dependent antigen
por: Jacque, Emilie, et al.
Publicado: (2014)

The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway
por: Schweighoffer, Edina, et al.
Publicado: (2013)

Porta themis fiscal 2004 /
por: Calvo Nicolau, Enrique
Publicado: (2004)

Micro Themis constitución política
por: Calvo Nicolau, Enrique
Publicado: (1989)

Miicro Themis Fiscal 1991
por: Calvo Nicolau, Enrique
Publicado: (1991)

The "CAT" project ("Cherenkov Array at Themis")
por: Degrange, B, et al.
Publicado: (1994)

Expression of heavy chain‐only antibodies can support B‐cell development in light chain knockout chickens
por: Schusser, Benjamin, et al.
Publicado: (2016)

Characteristics of the Flank Magnetopause: THEMIS Observations
por: Haaland, S., et al.
Publicado: (2019)

B-cell reconstitution after lentiviral vector–mediated gene therapy in patients with Wiskott-Aldrich syndrome
por: Castiello, Maria Carmina, et al.
Publicado: (2015)

Cherenkov array at Thémis: CAT project report
por: Degrange, B, et al.
Publicado: (1993)

Themis2/ICB1 Is a Signaling Scaffold That Selectively Regulates Macrophage Toll-Like Receptor Signaling and Cytokine Production
por: Peirce, Matthew J., et al.
Publicado: (2010)

Themis-associated phosphatase activity controls signaling in T cell development
por: Mehta, Monika, et al.
Publicado: (2018)

The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
por: Clement, Dennis, et al.
Publicado: (2023)

Plasmodium-specific atypical memory B cells are short-lived activated B cells
por: Pérez-Mazliah, Damián, et al.
Publicado: (2018)

Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency
por: Lang, Philipp A., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_brl80coasuct0mpquibg6kgn3b