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Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

Expression of the CTLA-4 gene is absolutely required for immune homeostasis, but aspects of its molecular nature remain undefined. In particular, the characterization of the soluble CTLA-4 (sCTLA-4) protein isoform generated by an alternatively spliced mRNA of CTLA4 lacking transmembrane-encoding ex...

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Detalles Bibliográficos
Autores principales:	Esposito, Laura, Hunter, Kara M. D., Clark, Jan, Rainbow, Daniel B., Stevens, Helen, Denesha, Jennifer, Duley, Simon, Dawson, Sarah, Coleman, Gillian, Nutland, Sarah, Bell, Gwynneth L., Moran, Carla, Pekalski, Marcin, Todd, John A., Wicker, Linda S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2014
Materias:	Molecular and Structural Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082723/ https://www.ncbi.nlm.nih.gov/pubmed/24928993 http://dx.doi.org/10.4049/jimmunol.1303389

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