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Quercetin Significantly Inhibits the Metabolism of Caffeine, a Substrate of Cytochrome P450 1A2 Unrelated to CYP1A2*1C (−2964G>A) and *1F (734C>A) Gene Polymorphisms
Background. Quercetin is abundant in plants and human diets. Previous studies indicated that quercetin inhibited the activity of CYP1A2, and the combination of quercetin with the substrates of CYP1A2 might produce herb-drug interactions. This research aims to determine the effects of quercetin and t...
Autores principales: | Xiao, Jian, Huang, Wei-Hua, Peng, Jing-Bo, Tan, Zhi-Rong, Ou-Yang, Dong-Sheng, Hu, Dong-Li, Zhang, Wei, Chen, Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082882/ https://www.ncbi.nlm.nih.gov/pubmed/25025048 http://dx.doi.org/10.1155/2014/405071 |
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