Cargando…
piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells
Transposable elements (TEs) occupy a large fraction of metazoan genomes and pose a constant threat to genomic integrity. This threat is particularly critical in germ cells, as changes in the genome that are induced by TEs will be transmitted to the next generation. Small noncoding piwi-interacting R...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083086/ https://www.ncbi.nlm.nih.gov/pubmed/24939875 http://dx.doi.org/10.1101/gad.240895.114 |