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A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection
BACKGROUND: Autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. Most of the cases are associated with viral or bacterial infections. In some cases, AIHA can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shahid Sadoughi University of Medical Sciences
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083205/ https://www.ncbi.nlm.nih.gov/pubmed/25002930 |
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author | Hosseeini, S Ansari, Sh Kalantar, E Sabzechian, M Alibeik, A Dorgalaleh, A |
author_facet | Hosseeini, S Ansari, Sh Kalantar, E Sabzechian, M Alibeik, A Dorgalaleh, A |
author_sort | Hosseeini, S |
collection | PubMed |
description | BACKGROUND: Autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. Most of the cases are associated with viral or bacterial infections. In some cases, AIHA can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus requiring prolonged immunosuppressive therapy. CASE REPORT: Especially in children younger than 2 years of age, the clinical course of the disease may show either resistance to steroids or dependence on high-dose steroids. We report here an infant fatal autoimmune CONCLUSION: This case suggests that investigation for the presence of CMV infection in infantile AIHA should be considered. Severe hemolysis is rare but could be a potentially life-threatening complication of CMV infection described mostly in immune compromised adults and children. |
format | Online Article Text |
id | pubmed-4083205 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Shahid Sadoughi University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-40832052014-07-07 A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection Hosseeini, S Ansari, Sh Kalantar, E Sabzechian, M Alibeik, A Dorgalaleh, A Iran J Ped Hematol Oncol Case Report BACKGROUND: Autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. Most of the cases are associated with viral or bacterial infections. In some cases, AIHA can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus requiring prolonged immunosuppressive therapy. CASE REPORT: Especially in children younger than 2 years of age, the clinical course of the disease may show either resistance to steroids or dependence on high-dose steroids. We report here an infant fatal autoimmune CONCLUSION: This case suggests that investigation for the presence of CMV infection in infantile AIHA should be considered. Severe hemolysis is rare but could be a potentially life-threatening complication of CMV infection described mostly in immune compromised adults and children. Shahid Sadoughi University of Medical Sciences 2014 2014-04-20 /pmc/articles/PMC4083205/ /pubmed/25002930 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Hosseeini, S Ansari, Sh Kalantar, E Sabzechian, M Alibeik, A Dorgalaleh, A A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection |
title | A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection |
title_full | A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection |
title_fullStr | A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection |
title_full_unstemmed | A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection |
title_short | A Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection |
title_sort | fetal hemolytic anemia in a child with cytomegalovirus infection |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083205/ https://www.ncbi.nlm.nih.gov/pubmed/25002930 |
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