FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR)

Adenosylcobalamin, the coenzyme form of vitamin B(12), is one Nature's most complex coenzyme whose de novo biogenesis proceeds along either an anaerobic or aerobic metabolic pathway. The aerobic synthesis involves reduction of the centrally chelated cobalt metal ion of the corrin ring from Co(I...

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Detalles Bibliográficos
Autores principales: Lawrence, Andrew D., Taylor, Samantha L., Scott, Alan, Rowe, Michelle L., Johnson, Christopher M., Rigby, Stephen E. J., Geeves, Michael A., Pickersgill, Richard W., Howard, Mark J., Warren, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083273/
https://www.ncbi.nlm.nih.gov/pubmed/24909839
http://dx.doi.org/10.1042/BSR20140060

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