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Aged Human Mesenchymal Stem Cells: The Duration of Bone Morphogenetic Protein-2 Stimulation Determines Induction or Inhibition of Osteogenic Differentiation

Bone morphogenetic protein 2 (BMP-2) is a potent osteoinductive cytokine and a growing number of in vitro studies analyze its effects on human mesenchymal stem cells (hMSC) derived from aged or osteoporotic donors. In these studies the exact quantification of osteogenic differentiation capacity is o...

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Detalles Bibliográficos
Autores principales:	Heggebö, Jostein, Haasters, Florian, Polzer, Hans, Schwarz, Christina, Saller, Maximilian Michael, Mutschler, Wolf, Schieker, Matthias, Prall, Wolf Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PAGEPress Publications, Pavia, Italy 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083304/ https://www.ncbi.nlm.nih.gov/pubmed/25002931 http://dx.doi.org/10.4081/or.2014.5242

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