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Design and optimization of bilayered tablet of Hydrochlorothiazide using the Quality-by-Design approach

AIM: The aim of the present study is to develop an optimize bilayered tablet using Hydrochlorothiazide (HCTZ) as a model drug candidate using quality by design (QbD) approach. INTRODUCTION AND METHOD: The bilayered tablet gives biphasic drug release through loading dose; prepared using croscarmellos...

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Detalles Bibliográficos
Autores principales:	Dholariya, Yatin N, Bansod, Yogesh B, Vora, Rahul M, Mittal, Sandeep S, Shirsat, Ajinath Eknath, Bhingare, Chandrashekhar L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2014
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083539/ https://www.ncbi.nlm.nih.gov/pubmed/25006554 http://dx.doi.org/10.4103/2230-973X.133058

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