Silibinin Inhibits ICAM-1 Expression via Regulation of N-Linked and O-Linked Glycosylation in ARPE-19 Cells

To evaluate the effects of silibinin on intercellular adhesion molecule-1 (ICAM-1) expression, we used ARPE-19 cells as a model in which tumor necrosis factor (TNF-α) and interferon (IFN-γ) enhanced ICAM-1 expression. This upregulation was inhibited by silibinin. In an adherence assay using ARPE-19...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yi-Hao, Chen, Ching-Long, Liang, Chang-Min, Liang, Jy-Been, Tai, Ming-Cheng, Chang, Yun-Hsiang, Lu, Da-Wen, Chen, Jiann-Torng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083610/
https://www.ncbi.nlm.nih.gov/pubmed/25032222
http://dx.doi.org/10.1155/2014/701395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083610/
https://www.ncbi.nlm.nih.gov/pubmed/25032222
http://dx.doi.org/10.1155/2014/701395

Ejemplares similares