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Silibinin Inhibits ICAM-1 Expression via Regulation of N-Linked and O-Linked Glycosylation in ARPE-19 Cells

To evaluate the effects of silibinin on intercellular adhesion molecule-1 (ICAM-1) expression, we used ARPE-19 cells as a model in which tumor necrosis factor (TNF-α) and interferon (IFN-γ) enhanced ICAM-1 expression. This upregulation was inhibited by silibinin. In an adherence assay using ARPE-19...

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Detalles Bibliográficos
Autores principales:	Chen, Yi-Hao, Chen, Ching-Long, Liang, Chang-Min, Liang, Jy-Been, Tai, Ming-Cheng, Chang, Yun-Hsiang, Lu, Da-Wen, Chen, Jiann-Torng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083610/ https://www.ncbi.nlm.nih.gov/pubmed/25032222 http://dx.doi.org/10.1155/2014/701395

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