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Vena Cava ınvasion by Adrenal Leiomyosarcoma
Primary adrenal mesenchymal tumors are extremely rare. These tumors are hard to diagnose, and similar to certain adrenal tumors, as they do not produce hormones, and they can only manifest themselves when the tumor reaches an advanced size. These tumors are generally detected incidentally. This stud...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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PAGEPress Publications, Pavia, Italy
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083666/ https://www.ncbi.nlm.nih.gov/pubmed/25002946 http://dx.doi.org/10.4081/rt.2014.5275 |
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author | Öztürk, Hakan |
author_facet | Öztürk, Hakan |
author_sort | Öztürk, Hakan |
collection | PubMed |
description | Primary adrenal mesenchymal tumors are extremely rare. These tumors are hard to diagnose, and similar to certain adrenal tumors, as they do not produce hormones, and they can only manifest themselves when the tumor reaches an advanced size. These tumors are generally detected incidentally. This study reports a rare case of primary leiomyosarcoma of the right adrenal gland with vena cava invasion, in a 70-year-old woman who presented with right flank pain. Computerized tomography showed an adrenal mass with a diameter of 78 mm, which exerted pressure on the vena cava inferior. The invasive part was excised by using adrenalectomy and cavatomy. Tumor invasion was determined on the wall of the vena cava. Histopathological examination on 10× magnification showed 8-10 mitotic events. Immunohistochemical staining showed that the cells were SMA (+), desmin (+), cytokeratin (-), and Bcl-2 (-). The Ki67 proliferation index was 70%. Widespread metastasis developed six months after the adrenalectomy. |
format | Online Article Text |
id | pubmed-4083666 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | PAGEPress Publications, Pavia, Italy |
record_format | MEDLINE/PubMed |
spelling | pubmed-40836662014-07-07 Vena Cava ınvasion by Adrenal Leiomyosarcoma Öztürk, Hakan Rare Tumors Case Report Primary adrenal mesenchymal tumors are extremely rare. These tumors are hard to diagnose, and similar to certain adrenal tumors, as they do not produce hormones, and they can only manifest themselves when the tumor reaches an advanced size. These tumors are generally detected incidentally. This study reports a rare case of primary leiomyosarcoma of the right adrenal gland with vena cava invasion, in a 70-year-old woman who presented with right flank pain. Computerized tomography showed an adrenal mass with a diameter of 78 mm, which exerted pressure on the vena cava inferior. The invasive part was excised by using adrenalectomy and cavatomy. Tumor invasion was determined on the wall of the vena cava. Histopathological examination on 10× magnification showed 8-10 mitotic events. Immunohistochemical staining showed that the cells were SMA (+), desmin (+), cytokeratin (-), and Bcl-2 (-). The Ki67 proliferation index was 70%. Widespread metastasis developed six months after the adrenalectomy. PAGEPress Publications, Pavia, Italy 2014-06-23 /pmc/articles/PMC4083666/ /pubmed/25002946 http://dx.doi.org/10.4081/rt.2014.5275 Text en ©Copyright H. Öztürk http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Öztürk, Hakan Vena Cava ınvasion by Adrenal Leiomyosarcoma |
title | Vena Cava ınvasion by Adrenal Leiomyosarcoma |
title_full | Vena Cava ınvasion by Adrenal Leiomyosarcoma |
title_fullStr | Vena Cava ınvasion by Adrenal Leiomyosarcoma |
title_full_unstemmed | Vena Cava ınvasion by Adrenal Leiomyosarcoma |
title_short | Vena Cava ınvasion by Adrenal Leiomyosarcoma |
title_sort | vena cava ınvasion by adrenal leiomyosarcoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083666/ https://www.ncbi.nlm.nih.gov/pubmed/25002946 http://dx.doi.org/10.4081/rt.2014.5275 |
work_keys_str_mv | AT ozturkhakan venacavaınvasionbyadrenalleiomyosarcoma |