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Modulation of cellular signaling pathways in P23H rhodopsin photoreceptors

We previously reported activation of the unfolded protein response (UPR) in P23H rhodopsin (RHO) retinas with autosomal dominant retinitis pigmentosa (ADRP). Knowing that the UPR can trigger Ca(2+) release from the endoplasmic reticulum and regulate cellular signaling we examined the level of Ca(2+)...

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Detalles Bibliográficos
Autores principales: Sizova, Olga S., Shinde, Vishal M., Lenox, Austin R., Gorbatyuk, Marina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083739/
https://www.ncbi.nlm.nih.gov/pubmed/24378535
http://dx.doi.org/10.1016/j.cellsig.2013.12.008

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