Cargando…

Corticosteroid treatment for community-acquired pneumonia - the STEP trial: study protocol for a randomized controlled trial

BACKGROUND: Community-acquired pneumonia (CAP) is the third-leading infectious cause of death worldwide. The standard treatment of CAP has not changed for the past fifty years and its mortality and morbidity remain high despite adequate antimicrobial treatment. Systemic corticosteroids have anti-inf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Blum, Claudine A, Nigro, Nicole, Winzeler, Bettina, Suter-Widmer, Isabelle, Schuetz, Philipp, Briel, Matthias, Bingisser, Roland, Zimmerli, Werner, Ullmer, Elke, Elsaesser, Hanno, Tarr, Philip, Wirz, Sebastian, Thomann, Robert, Hofmann, Eveline, Rodondi, Nicolas, Duplain, Hervé, Burki, Dieter, Mueller, Beat, Christ-Crain, Mirjam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083867/ https://www.ncbi.nlm.nih.gov/pubmed/24974155 http://dx.doi.org/10.1186/1745-6215-15-257

Ejemplares similares

Adjunct prednisone therapy for patients with community-acquired pneumonia: a randomized, placebo-controlled multicenter trial
por: Blum, CA, et al.
Publicado: (2015)

Influence of Prednisone on Inflammatory Biomarkers in Community‐Acquired Pneumonia: Secondary Analysis of a Randomized Trial
por: Raess, Natalie, et al.
Publicado: (2021)

Predictors for length of hospital stay in patients with community-acquired Pneumonia: Results from a Swiss Multicenter study
por: Suter-Widmer, Isabelle, et al.
Publicado: (2012)

Procalcitonin guided antibiotic therapy and hospitalization in patients with lower respiratory tract infections: a prospective, multicenter, randomized controlled trial
por: Schuetz, Philipp, et al.
Publicado: (2007)

Pre-analytic factors and initial biomarker levels in community-acquired pneumonia patients
por: Kutz, Alexander, et al.
Publicado: (2014)

Copeptin levels and commonly used laboratory parameters in hospitalised patients with severe hypernatraemia - the “Co-MED study”
por: Nigro, Nicole, et al.
Publicado: (2018)

Association of the Tyrosine/Nitrotyrosine pathway with death or ICU admission within 30 days for patients with community acquired pneumonia
por: Baumgartner, Thomas, et al.
Publicado: (2018)

Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections
por: Schuetz, Philipp, et al.
Publicado: (2010)

The National Early Warning Score (NEWS) for outcome prediction in emergency department patients with community-acquired pneumonia: results from a 6-year prospective cohort study
por: Sbiti-Rohr, Diana, et al.
Publicado: (2016)

Association of Adrenal Function and Disease Severity in Community-Acquired Pneumonia
por: Mueller, Cornelia, et al.
Publicado: (2014)

Effect of procalcitonin-based guidelines compared with standard guidelines on antibiotic use in lower respiratory tract infections: the randomized-controlled multicenter ProHOSP trial
por: Schuetz, P, et al.
Publicado: (2009)

Copeptin for risk stratification in non-traumatic headache in the emergency setting: a prospective multicenter observational cohort study
por: Blum, Claudine Angela, et al.
Publicado: (2017)

Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671]
por: Briel, Matthias, et al.
Publicado: (2005)

Hyponatremia and anti-diuretic hormone in Legionnaires’ disease
por: Schuetz, Philipp, et al.
Publicado: (2013)

Time-dependent association of glucocorticoids with adverse outcome in community-acquired pneumonia: a 6-year prospective cohort study
por: Nickler, Manuela, et al.
Publicado: (2017)

Infection biomarkers in primary care patients with acute respiratory tract infections–comparison of Procalcitonin and C-reactive protein
por: Meili, Marc, et al.
Publicado: (2016)

Prognostic Value of Dehydroepiandrosterone-Sulfate and Other Parameters of Adrenal Function in Acute Ischemic Stroke
por: Blum, Claudine A., et al.
Publicado: (2013)

No obesity paradox in patients with community-acquired pneumonia – secondary analysis of a randomized controlled trial
por: Borisov, Angel N., et al.
Publicado: (2022)

Dihydrotestosterone is a predictor for mortality in males with community-acquired pneumonia: results of a 6-year follow-up study
por: Zurfluh, Seline, et al.
Publicado: (2018)

Association of adrenal insufficiency with patient-oriented health-care outcomes in adult medical inpatients
por: Ebrahimi, Fahim, et al.
Publicado: (2019)

Admission levels of asymmetric and symmetric dimethylarginine predict long-term outcome in patients with community-acquired pneumonia
por: Vögeli, Alaadin, et al.
Publicado: (2017)

Endothelin-1 precursor peptides correlate with severity of disease and outcome in patients with community acquired pneumonia
por: Schuetz, Philipp, et al.
Publicado: (2008)

Which patients with lower respiratory tract infections need inpatient treatment? Perceptions of physicians, nurses, patients and relatives
por: Baehni, Claudia, et al.
Publicado: (2010)

Pro-Adrenomedullin predicts 10-year all-cause mortality in community-dwelling patients: a prospective cohort study
por: Odermatt, Jonas, et al.
Publicado: (2017)

BNP but Not s-cTnln Is Associated with Cardioembolic Aetiology and Predicts Short and Long Term Prognosis after Cerebrovascular Events
por: Nigro, Nicole, et al.
Publicado: (2014)

Effects of interleukin-1 antagonism on cortisol levels in individuals with obesity: a randomized clinical trial
por: Ebrahimi, Fahim, et al.
Publicado: (2019)

Copeptin Levels Remain Unchanged during the Menstrual Cycle
por: Blum, Claudine A., et al.
Publicado: (2014)

Mannose-Binding Lectin Deficiency Is Associated With Smaller Infarction Size and Favorable Outcome in Ischemic Stroke Patients
por: Osthoff, Michael, et al.
Publicado: (2011)

Enhancement of CURB65 score with proadrenomedullin (CURB65-A) for outcome prediction in lower respiratory tract infections: Derivation of a clinical algorithm
por: Albrich, Werner C, et al.
Publicado: (2011)

Copeptin and its role in the diagnosis of diabetes insipidus and the syndrome of inappropriate antidiuresis
por: Refardt, Julie, et al.
Publicado: (2019)

Approach to the Patient: “Utility of the Copeptin Assay”
por: Christ-Crain, Mirjam, et al.
Publicado: (2022)

Copeptin is not useful as a marker of malignant disease in the syndrome of inappropriate antidiuresis
por: Winzeler, Bettina, et al.
Publicado: (2019)

Circulating Precursor Levels of Endothelin-1 and Adrenomedullin, Two Endothelium-Derived, Counteracting Substances, in Sepsis
por: Schuetz, Philipp, et al.
Publicado: (2007)

Diagnostic and prognostic accuracy of clinical and laboratory parameters in community-acquired pneumonia
por: Müller, Beat, et al.
Publicado: (2007)

RF25 | PMON179 Role of Apparent Strong Ion Difference in the Differential Diagnosis of Thiazide Associated Hyponatremia
por: Monnerat, Sophie, et al.
Publicado: (2022)

FRI068 Gender Differences In Smoking Cessation? Results Of A Randomized Controlled Trial Of Dulaglutide-assisted Smoking Cessation
por: Baur, Fabienne, et al.
Publicado: (2023)

Effects of interleukin-1 antagonism and corticosteroids on fibroblast growth factor-21 in patients with metabolic syndrome
por: Ebrahimi, Fahim, et al.
Publicado: (2021)

SAT-066 Effect Of Interleukin-1-receptor Antagonist On Hemodynamics And Renin-angiotensin-aldosterone System In Obese Individuals
por: Urwyler, Sandrine, et al.
Publicado: (2019)

Empagliflozin Increases Short-Term Urinary Volume Output in Artificially Induced Syndrome of Inappropriate Antidiuresis
por: Refardt, Julie, et al.
Publicado: (2017)

Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia [ISRCTN04176397]
por: Christ-Crain, Mirjam, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_6jn5iqlh6iutf963ehejsfgm97