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Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus

This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dr...

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Detalles Bibliográficos
Autores principales: Razmavar, Somayeh, Abdulla, Mahmood Ameen, Ismail, Salmah Binti, Hassandarvish, Pouya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083884/
https://www.ncbi.nlm.nih.gov/pubmed/25028658
http://dx.doi.org/10.1155/2014/521287
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author Razmavar, Somayeh
Abdulla, Mahmood Ameen
Ismail, Salmah Binti
Hassandarvish, Pouya
author_facet Razmavar, Somayeh
Abdulla, Mahmood Ameen
Ismail, Salmah Binti
Hassandarvish, Pouya
author_sort Razmavar, Somayeh
collection PubMed
description This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dried, powdered, and extracted using solvent ethanol. Preliminary phytochemical screening of the crude extracts revealed the presence of alkaloids, flavonoids, steroids, terpenoids, phenols, and carbohydrates. The presence of these bioactive constituents is related to the antibacterial activity of the plant. Disc diffusion method revealed a high degree of activity against microorganisms. The results confirm that Baeckea frutescens L. can be used as a source of drugs to fight infections caused by susceptible bacteria.
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spelling pubmed-40838842014-07-15 Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus Razmavar, Somayeh Abdulla, Mahmood Ameen Ismail, Salmah Binti Hassandarvish, Pouya Biomed Res Int Research Article This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dried, powdered, and extracted using solvent ethanol. Preliminary phytochemical screening of the crude extracts revealed the presence of alkaloids, flavonoids, steroids, terpenoids, phenols, and carbohydrates. The presence of these bioactive constituents is related to the antibacterial activity of the plant. Disc diffusion method revealed a high degree of activity against microorganisms. The results confirm that Baeckea frutescens L. can be used as a source of drugs to fight infections caused by susceptible bacteria. Hindawi Publishing Corporation 2014 2014-06-16 /pmc/articles/PMC4083884/ /pubmed/25028658 http://dx.doi.org/10.1155/2014/521287 Text en Copyright © 2014 Somayeh Razmavar et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Razmavar, Somayeh
Abdulla, Mahmood Ameen
Ismail, Salmah Binti
Hassandarvish, Pouya
Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_full Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_fullStr Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_full_unstemmed Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_short Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_sort antibacterial activity of leaf extracts of baeckea frutescens against methicillin-resistant staphylococcus aureus
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083884/
https://www.ncbi.nlm.nih.gov/pubmed/25028658
http://dx.doi.org/10.1155/2014/521287
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