Cargando…

Inhibitory effects of prostaglandin E(2) on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma

BACKGROUND: Several studies have described an increased cyclooxygenase-2 (COX-2) expression in pancreatic cancer, but the role of COX-2 in tumour development and progression is not clear. The aim of the present study was to examine expression of COX-2 in cancer cells and stromal cells in pancreatic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pomianowska, Ewa, Sandnes, Dagny, Grzyb, Krzysztof, Schjølberg, Aasa R, Aasrum, Monica, Tveteraas, Ingun H, Tjomsland, Vegard, Christoffersen, Thoralf, Gladhaug, Ivar P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084579/ https://www.ncbi.nlm.nih.gov/pubmed/24912820 http://dx.doi.org/10.1186/1471-2407-14-413

Ejemplares similares

The TGFβ-SMAD3 pathway inhibits IL-1α induced interactions between human pancreatic stellate cells and pancreatic carcinoma cells and restricts cancer cell migration
por: Tjomsland, Vegard, et al.
Publicado: (2016)

Profile of MMP and TIMP Expression in Human Pancreatic Stellate Cells: Regulation by IL-1α and TGFβ and Implications for Migration of Pancreatic Cancer Cells()
por: Tjomsland, Vegard, et al.
Publicado: (2016)

Functional heterogeneity in tumor-derived human pancreatic stellate cells: Differential expression of HGF and implications for mitogenic signaling and migration in pancreatic cancer cells
por: Tjomsland, Vegard, et al.
Publicado: (2017)

Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells
por: Brusevold, Ingvild J, et al.
Publicado: (2014)

Mechanisms involved in PGE(2)-induced transactivation of the epidermal growth factor receptor in MH(1)C(1) hepatocarcinoma cells
por: Tveteraas, Ingun Heiene, et al.
Publicado: (2012)

Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells
por: Müller, Kristin M, et al.
Publicado: (2011)

COX-2 overexpression in resected pancreatic head adenocarcinomas correlates with favourable prognosis
por: Pomianowska, Ewa, et al.
Publicado: (2014)

Secretion of fibronectin by human pancreatic stellate cells promotes chemoresistance to gemcitabine in pancreatic cancer cells
por: Amrutkar, Manoj, et al.
Publicado: (2019)

Commonly Used Pancreatic Stellate Cell Cultures Differ Phenotypically and in Their Interactions with Pancreatic Cancer Cells
por: Lenggenhager, Daniela, et al.
Publicado: (2019)

Ca(2+)-mediated activation of ERK in hepatocytes by norepinephrine and prostaglandin F(2α): role of calmodulin and src kinases
por: Melien, Øyvind, et al.
Publicado: (2002)

Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing
por: Amrutkar, Manoj, et al.
Publicado: (2020)

Establishment and Characterization of Paired Primary Cultures of Human Pancreatic Cancer Cells and Stellate Cells Derived from the Same Tumor
por: Amrutkar, Manoj, et al.
Publicado: (2020)

Pancreatic stellate cell-induced gemcitabine resistance in pancreatic cancer is associated with LDHA- and MCT4-mediated enhanced glycolysis
por: Amrutkar, Manoj, et al.
Publicado: (2023)

Stellate Cells Aid Growth-Permissive Metabolic Reprogramming and Promote Gemcitabine Chemoresistance in Pancreatic Cancer
por: Amrutkar, Manoj, et al.
Publicado: (2021)

Differentiation markers in pancreatic head adenocarcinomas: MUC1 and MUC4 expression indicates poor prognosis in pancreatobiliary differentiated tumours
por: Westgaard, Arne, et al.
Publicado: (2009)

MicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor
por: Kuninty, Praneeth R., et al.
Publicado: (2016)

Targeting 15d-Prostaglandin J(2) to Hepatic Stellate Cells: Two Options Evaluated
por: Hagens, Werner I., et al.
Publicado: (2007)

Inhibitory Effect of Tanshinone IIA on Rat Hepatic Stellate Cells
por: Liu, Ya-Wei, et al.
Publicado: (2014)

Identification of an inhibitory neuron subtype, the L-stellate cell of the cochlear nucleus
por: Ngodup, Tenzin, et al.
Publicado: (2020)

The inhibitory effect of TU-100 on hepatic stellate cell activation in the tumor microenvironment
por: Wada, Yuma, et al.
Publicado: (2020)

Pancreatic Cancer Chemoresistance to Gemcitabine
por: Amrutkar, Manoj, et al.
Publicado: (2017)

Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors
por: Burum-Auensen, Espen, et al.
Publicado: (2010)

Alpha-single chains of collagen type VI inhibit the fibrogenic effects of triple helical collagen VI in hepatic stellate cells
por: Freise, Christian, et al.
Publicado: (2021)

Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells
por: Chen, Jennifer Y., et al.
Publicado: (2017)

Semi Mature Blood Dendritic Cells Exist in Patients with Ductal Pancreatic Adenocarcinoma Owing to Inflammatory Factors Released from the Tumor
por: Tjomsland, Vegard, et al.
Publicado: (2010)

Pancreatic stellate cells promote hapto-migration of cancer cells through collagen I-mediated signalling pathway
por: Lu, J, et al.
Publicado: (2014)

Thromboxane A(2) receptor contributes to the activation of rat pancreatic stellate cells induced by 8-epi-prostaglandin F(2α)
por: Zhang, Xiao-Li, et al.
Publicado: (2020)

Inhibitory Effects of Ecklonia cava Extract on High Glucose-Induced Hepatic Stellate Cell Activation
por: Yokogawa, Kumiko, et al.
Publicado: (2011)

Epimorphin Alters the Inhibitory Effects of SOX9 on Mmp13 in Activated Hepatic Stellate Cells
por: Pritchett, James, et al.
Publicado: (2014)

Inhibitory Smads suppress pancreatic stellate cell activation through negative feedback in chronic pancreatitis
por: Lin, Hao, et al.
Publicado: (2021)

Effect of prostaglandins and hormones on cyclic AMP formation in rat hepatomas and liver tissue.
por: Brønstad, G. O., et al.
Publicado: (1978)

Inhibitory effects of prostaglandin EP(4 )receptors on human eosinophils
por: Luschnig-Schratl, Petra, et al.
Publicado: (2009)

ARHGEF4-mediates the actin cytoskeleton reorganization of hepatic stellate cells in 3-dimensional collagen matrices
por: Zhang, Xiaowei, et al.
Publicado: (2019)

Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis
por: Min, Kyounghee, et al.
Publicado: (2023)

A Transcriptional Sequencing Analysis of Islet Stellate Cell and Pancreatic Stellate Cell
por: Wang, Xiaohang, et al.
Publicado: (2018)

Evidence for the involvement of G(i2) in activation of extracellular signal-regulated kinases in hepatocytes
por: Melien, Øyvind, et al.
Publicado: (2001)

IL-1α Expression in Pancreatic Ductal Adenocarcinoma Affects the Tumor Cell Migration and Is Regulated by the p38MAPK Signaling Pathway
por: Tjomsland, Vegard, et al.
Publicado: (2013)

Ionone Derivatives from the Mycelium of Phellinus linteus and the Inhibitory Effect on Activated Rat Hepatic Stellate Cells
por: Huang, Shiow-Chyn, et al.
Publicado: (2016)

Carvedilol improves liver cirrhosis in rats by inhibiting hepatic stellate cell activation, proliferation, invasion and collagen synthesis
por: Ling, Liping, et al.
Publicado: (2019)

Placebo effects in trials evaluating 12 selected minimally invasive interventions: a systematic review and meta-analysis
por: Holtedahl, Robin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2bq9onm29pui1dva9edi115mv1