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High-Dose Methotrexate for the Treatment of Relapsed Central Nervous System Erdheim-Chester Disease
Erdheim-Chester disease (ECD) is a rare multisystem non-Langerhans histiocytosis. CNS involvement is a major complication, which is often rapidly progressive and confers a poor prognosis. However, treatment of CNS ECD is difficult due to poor CNS penetrance by the most effective chemotherapeutic dru...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084618/ https://www.ncbi.nlm.nih.gov/pubmed/25031876 http://dx.doi.org/10.1155/2014/269359 |