Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes

BACKGROUND: Subtle functional deficiencies in highly conserved DNA repair or growth regulatory processes resulting from polymorphic variation may increase genetic susceptibility to breast cancer. Polymorphisms in DNA repair genes can impact protein function leading to genomic instability facilitated...

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Detalles Bibliográficos
Autores principales: Sigurdson, Alice J, Hauptmann, Michael, Chatterjee, Nilanjan, Alexander, Bruce H, Doody, Michele Morin, Rutter, Joni L, Struewing, Jeffery P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC408462/
https://www.ncbi.nlm.nih.gov/pubmed/15113441
http://dx.doi.org/10.1186/1471-2407-4-9

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