Cargando…

Melatonin Inhibits the Migration of Human Lung Adenocarcinoma A549 Cell Lines Involving JNK/MAPK Pathway

OBJECTIVE: Melatonin, an indolamine produced and secreted predominately by the pineal gland, exhibits a variety of physiological functions, possesses antioxidant and antitumor properties. But, the mechanisms for the anti-cancer effects are unknown. The present study explored the effects of melatonin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Qiaoyun, Gui, Shuyu, Zhou, Qing, Wang, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084631/ https://www.ncbi.nlm.nih.gov/pubmed/24992189 http://dx.doi.org/10.1371/journal.pone.0101132

Ejemplares similares

Inhibition of cell migration by ouabain in the A549 human lung cancer cell line
por: LIU, NING, et al.
Publicado: (2013)

XAV939 inhibits the proliferation and migration of lung adenocarcinoma A549 cells through the WNT pathway
por: Li, Chong, et al.
Publicado: (2018)

XBP1s promotes the development of lung adenocarcinoma via the p-JNK MAPK pathway
por: Jiang, Hongxia, et al.
Publicado: (2022)

Interaction with adipocytes induces lung adenocarcinoma A549 cell migration and tumor growth
por: Li, Fan-Fan, et al.
Publicado: (2018)

EGF Induces Migration Independent of EMT or Invasion in A549 Lung Adenocarcinoma Cells
por: Schelch, Karin, et al.
Publicado: (2021)

Altered Mitochondrial Dynamics, Biogenesis, and Functions in the Paclitaxel-Resistant Lung Adenocarcinoma Cell Line A549/Taxol
por: Zhou, Xiang, et al.
Publicado: (2020)

Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1/2 and p38 MAPK pathways
por: MIN, JIE, et al.
Publicado: (2015)

Melatonin Enhances Palladium-Nanoparticle-Induced Cytotoxicity and Apoptosis in Human Lung Epithelial Adenocarcinoma Cells A549 and H1229
por: Gurunathan, Sangiliyandi, et al.
Publicado: (2020)

Alpha-mangostin inhibits the migration and invasion of A549 lung cancer cells
por: Phan, Thi Kieu Trang, et al.
Publicado: (2018)

Curcumin induced autophagy anticancer effects on human lung adenocarcinoma cell line A549
por: Liu, Furong, et al.
Publicado: (2017)

Melatonin inhibits colon cancer RKO cell migration by downregulating Rho-associated protein kinase expression via the p38/MAPK signaling pathway
por: Liu, Zhen, et al.
Publicado: (2017)

Cholesterol biosynthesis inhibitor RO 48-8071 inhibits pancreatic ductal adenocarcinoma cell viability by deactivating the JNK and ERK/MAPK signaling pathway
por: Ding, Zhen, et al.
Publicado: (2021)

Aprepitant Inhibits JNK and p38/MAPK to Attenuate Inflammation and Suppresses Inflammatory Pain
por: Yang, Yang, et al.
Publicado: (2022)

In vivo and in vitro effects of hyperplasia suppressor gene on the proliferation and apoptosis of lung adenocarcinoma A549 cells
por: Sun, Zhen-Qing, et al.
Publicado: (2018)

MAPK/JNK signalling: a potential autophagy regulation pathway
por: Zhou, Yuan-Yuan, et al.
Publicado: (2015)

Establishment of Cell Lines with High and Low Metastatic Potential from A549 Human Lung Adenocarcinoma
por: Shindo‐Okada, Nobuko, et al.
Publicado: (2002)

Role of the MAPK pathway in human lung epithelial-like A549 cells apoptosis induced by paraquat
por: Sun, Da-Zhuang, et al.
Publicado: (2020)

Effect of receptor for hyaluronan-mediated motility inhibition on radiosensitivity of lung adenocarcinoma A549 cells
por: Gao, Chunzi, et al.
Publicado: (2019)

Indomethacin-Enhanced Anticancer Effect of Arsenic Trioxide in A549 Cell Line: Involvement of Apoptosis and Phospho-ERK and p38 MAPK Pathways
por: Mandegary, Ali, et al.
Publicado: (2013)

Anticancer property of gallic acid in A549, a human lung adenocarcinoma cell line, and possible mechanisms
por: Maurya, Dharmendra K., et al.
Publicado: (2011)

The synergistic effect of propofol and ulinastatin suppressed the viability of the human lung adenocarcinoma epithelial A549 cell line
por: Li, Ping, et al.
Publicado: (2018)

Cytotoxicity, Apoptosis, Migration Inhibition, and Autophagy-Induced by Crude Ricin from Ricinus communis Seeds in A549 Lung Cancer Cell Lines
por: Herawati, Irma Erika, et al.
Publicado: (2022)

Down-Regulation of AHNAK2 Inhibits Cell Proliferation, Migration and Invasion Through Inactivating the MAPK Pathway in Lung Adenocarcinoma
por: Wang, Dong-Wei, et al.
Publicado: (2020)

Benzo(a)pyrene enhances the EMT-associated migration of lung adenocarcinoma A549 cells by upregulating Twist1
por: Chen, Xi, et al.
Publicado: (2017)

Identification of side population cells in human lung adenocarcinoma A549 cell line and elucidation of the underlying roles in lung cancer
por: Xie, Tong, et al.
Publicado: (2018)

Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells
por: Eguchi, Hiroaki, et al.
Publicado: (2018)

Upregulation of miR-146a increases cisplatin sensitivity of the non-small cell lung cancer A549 cell line by targeting JNK-2
por: Pang, Linrong, et al.
Publicado: (2017)

Effect of inhibition proliferation in human lung adenocarcinoma A549 cells by cytokine-induced killer cells
por: Li, Dengrui, et al.
Publicado: (2015)

Ocimum sanctum Linn. ethanolic extract inhibits angiogenesis in human lung adenocarcinoma (a549) cells
por: Wihadmadyatami, Hevi, et al.
Publicado: (2020)

Klotho inhibits growth and promotes apoptosis in human lung cancer cell line A549
por: Chen, Bo, et al.
Publicado: (2010)

Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cells
por: Taylor, Catherine A, et al.
Publicado: (2013)

Hypoxia Activates Notch4 via ERK/JNK/P38 MAPK Signaling Pathways to Promote Lung Adenocarcinoma Progression and Metastasis
por: Li, Xiaochen, et al.
Publicado: (2021)

Chemosensitivity of radioresistant cells in the multicellular spheroids of A549 lung adenocarcinoma
por: Shi, Degang, et al.
Publicado: (2009)

Resveratrol Affects Sphingolipid Metabolism in A549 Lung Adenocarcinoma Cells
por: Momchilova, Albena, et al.
Publicado: (2022)

Inhibitory effect of O-propargyllawsone in A549 lung adenocarcinoma cells
por: dos Santos, Edmilson Willian Propheta, et al.
Publicado: (2023)

Comparison of oxycodone and morphine on the proliferation, apoptosis and expression of related molecules in the A549 human lung adenocarcinoma cell line
por: Tian, Mi, et al.
Publicado: (2016)

Alcohol Extract of YFXJ Decoction Reverses the Drug Resistance of Human Lung Adenocarcinoma Cell Line A549/DDP
por: Liu, Zhongliang, et al.
Publicado: (2022)

STIM1 silencing inhibits the migration and invasion of A549 cells
por: Wang, Yadong, et al.
Publicado: (2017)

MicroRNA-155-5p suppresses the migration and invasion of lung adenocarcinoma A549 cells by targeting Smad2
por: Lin, Jianfeng, et al.
Publicado: (2018)

Effect of silencing SATB1 on proliferation, invasion and apoptosis of A549 human lung adenocarcinoma cells
por: Huang, Bo, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_k4nflubjm9imiul0vbn5rtu35o