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Transplanting Supersites of HIV-1 Vulnerability

One strategy for isolating or eliciting antibodies against a specific target region on the envelope glycoprotein trimer (Env) of the human immunodeficiency virus type 1 (HIV-1) involves the creation of site transplants, which present the target region on a heterologous protein scaffold with preserve...

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Detalles Bibliográficos
Autores principales: Zhou, Tongqing, Zhu, Jiang, Yang, Yongping, Gorman, Jason, Ofek, Gilad, Srivatsan, Sanjay, Druz, Aliaksandr, Lees, Christopher R., Lu, Gabriel, Soto, Cinque, Stuckey, Jonathan, Burton, Dennis R., Koff, Wayne C., Connors, Mark, Kwon, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084637/
https://www.ncbi.nlm.nih.gov/pubmed/24992528
http://dx.doi.org/10.1371/journal.pone.0099881