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Locating the Route of Entry and Binding Sites of Benzocaine and Phenytoin in a Bacterial Voltage Gated Sodium Channel

Sodium channel blockers are used to control electrical excitability in cells as a treatment for epileptic seizures and cardiac arrhythmia, and to provide short term control of pain. Development of the next generation of drugs that can selectively target one of the nine types of voltage-gated sodium...

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Detalles Bibliográficos
Autores principales: Martin, Lewis J., Corry, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084639/
https://www.ncbi.nlm.nih.gov/pubmed/24992293
http://dx.doi.org/10.1371/journal.pcbi.1003688