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Genome-Wide Association Study of Celiac Disease in North America Confirms FRMD4B as New Celiac Locus

We performed a genome-wide association study (GWAS) of 1550 North American celiac disease cases and 3084 controls. Twelve SNPs, distributed across four regions (3p21.31, 4q27, 6q15, 6q25), were significantly associated with disease (p-value <1.0×10(−7)), and a further seven SNPs, across four addi...

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Detalles Bibliográficos
Autores principales: Garner, Chad, Ahn, Richard, Ding, Yuan Chun, Steele, Linda, Stoven, Samantha, Green, Peter H., Fasano, Alessio, Murray, Joseph A., Neuhausen, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084811/
https://www.ncbi.nlm.nih.gov/pubmed/24999842
http://dx.doi.org/10.1371/journal.pone.0101428