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Autocrine Effects of Tumor-Derived Complement

We describe a role for the complement system in enhancing cancer growth. Cancer cells secrete complement proteins that stimulate tumor growth upon activation. Complement promotes tumor growth via a direct autocrine effect that is partially independent of tumor-infiltrating cytotoxic T cells. Activat...

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Detalles Bibliográficos
Autores principales:	Cho, Min Soon, Vasquez, Hernan G., Rupaimoole, Rajesha, Pradeep, Sunila, Wu, Sherry, Zand, Behrouz, Han, Hee-Dong, Rodriguez-Aguayo, Cristian, Bottsford-Miller, Justin, Huang, Jie, Miyake, Takahito, Choi, Hyun-Jin, Dalton, Heather J., Ivan, Cristina, Baggerly, Keith, Lopez-Berestein, Gabriel, Sood, Anil K., Afshar-Kharghan, Vahid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084868/ https://www.ncbi.nlm.nih.gov/pubmed/24613353 http://dx.doi.org/10.1016/j.celrep.2014.02.014

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