Microenvironmental Stiffness Enhances Glioma Cell Proliferation by Stimulating Epidermal Growth Factor Receptor Signaling

The aggressive and rapidly lethal brain tumor glioblastoma (GBM) is associated with profound tissue stiffening and genomic lesions in key members of the epidermal growth factor receptor (EGFR) pathway. Previous studies from our laboratory have shown that increasing microenvironmental stiffness in cu...

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Detalles Bibliográficos
Autores principales: Umesh, Vaibhavi, Rape, Andrew D., Ulrich, Theresa A., Kumar, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084995/
https://www.ncbi.nlm.nih.gov/pubmed/25000176
http://dx.doi.org/10.1371/journal.pone.0101771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084995/
https://www.ncbi.nlm.nih.gov/pubmed/25000176
http://dx.doi.org/10.1371/journal.pone.0101771

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