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Chronopharmacology and Mechanism of Antitumor Effect of Erlotinib in Lewis Tumor-Bearing Mice

The epidermal growth factor receptor (EGFR), a ubiquitously expressed receptor tyrosine kinase, is recognized as a key mediator of tumorigenesis in many human epithelial tumors. Erlotinib is tyrosine kinase inhibitor approved by FDA for use in oncology. It inhibits the intracellular phosphorylation...

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Detalles Bibliográficos
Autores principales:	Wang, Peipei, An, Fengmei, Zhuang, Xingjun, Liu, Jiao, Zhao, Liyan, Zhang, Bin, Liu, Liang, Lin, Pingping, Li, Mingchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085002/ https://www.ncbi.nlm.nih.gov/pubmed/25000529 http://dx.doi.org/10.1371/journal.pone.0101720

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