Distal Renal Tubules Are Deficient in Aggresome Formation and Autophagy upon Aldosterone Administration

Prolonged elevations of plasma aldosterone levels are associated with renal pathogenesis. We hypothesized that renal distress could be imposed by an augmented aldosterone-induced protein turnover challenging cellular protein degradation systems of the renal tubular cells. Cellular accumulation of sp...

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Detalles Bibliográficos
Autores principales: Cheema, Muhammad Umar, Damkier, Helle Hasager, Nielsen, Jakob, Poulsen, Ebbe Toftgaard, Enghild, Jan J., Fenton, Robert A., Praetorius, Jeppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085037/
https://www.ncbi.nlm.nih.gov/pubmed/25000288
http://dx.doi.org/10.1371/journal.pone.0101258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085037/
https://www.ncbi.nlm.nih.gov/pubmed/25000288
http://dx.doi.org/10.1371/journal.pone.0101258

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