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Distal Renal Tubules Are Deficient in Aggresome Formation and Autophagy upon Aldosterone Administration
Prolonged elevations of plasma aldosterone levels are associated with renal pathogenesis. We hypothesized that renal distress could be imposed by an augmented aldosterone-induced protein turnover challenging cellular protein degradation systems of the renal tubular cells. Cellular accumulation of sp...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085037/ https://www.ncbi.nlm.nih.gov/pubmed/25000288 http://dx.doi.org/10.1371/journal.pone.0101258 |