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Asymmetric Effect of Mechanical Stress on the Forward and Reverse Reaction Catalyzed by an Enzyme
The concept of modulating enzymatic activity by exerting a mechanical stress on the enzyme has been established in previous work. Mechanical perturbation is also a tool for probing conformational motion accompanying the enzymatic cycle. Here we report measurements of the forward and reverse kinetics...
Autores principales: | Joseph, Collin, Tseng, Chiao-Yu, Zocchi, Giovanni, Tlusty, Tsvi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085160/ https://www.ncbi.nlm.nih.gov/pubmed/25000118 http://dx.doi.org/10.1371/journal.pone.0101442 |
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