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Asymmetric Effect of Mechanical Stress on the Forward and Reverse Reaction Catalyzed by an Enzyme

The concept of modulating enzymatic activity by exerting a mechanical stress on the enzyme has been established in previous work. Mechanical perturbation is also a tool for probing conformational motion accompanying the enzymatic cycle. Here we report measurements of the forward and reverse kinetics...

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Detalles Bibliográficos
Autores principales: Joseph, Collin, Tseng, Chiao-Yu, Zocchi, Giovanni, Tlusty, Tsvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085160/
https://www.ncbi.nlm.nih.gov/pubmed/25000118
http://dx.doi.org/10.1371/journal.pone.0101442

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